For Systems Engineers coming in from PHP world, installing and configuring the software stack needed to run python + django applications can be a daunting task specially when dealing with multiple python versions. Or, when the operating system python version is not compatible with what is required by the python web application. Here's how I did it with Ubuntu:

1. Set locale and timezone

   locale-gen en_US.UTF-8
   echo "Asia/Singapore" >  /etc/timezone
   dpkg-reconfigure --frontend noninteractive tzdata

2. Update packages

   apt-get update && apt-get upgrade -y

3. Limits

   ulimit -n 20000
   echo 'fs.file-max = 200000' >> /etc/sysctl.d/20_nginx.conf